Tag: Grace Science Foundation

Developing an NGLY1 worm screen

Developing an NGLY1 worm screen

In 2016, Perlara and Grace Science Foundation launched a PerlQuest for NGLY1 Deficiency (also known as NGLY1-CDDG). As a part of this collaboration, we have embarked on developing an NGLY1 worm screen. This post will detail the worm team’s latest progress toward...
Perlara Open Finances 2017

Perlara Open Finances 2017

When we last checked in a year ago, Perlara had just achieved three critical milestones: a product (PerlQuest), a validating Pharma deal, and first revenue – a small check, but revenue nonetheless. Over the course of 2017, we transitioned from startup with a...
CRISPR genome editing to make an NGLY1 fly

CRISPR genome editing to make an NGLY1 fly

N-glycanase 1 deficiency, or “NGLY1,” is a rare genetic disorder arising from mutations in the ngly1 gene.  The disease was recently diagnosed in what was a remarkable partnering of patient advocates and scientists who used DNA sequencing to trace the disease-causing...
Translate »