Optimizing my first High Throughput Screen

Optimizing my first High Throughput Screen

I, along with Nina, performed our first high-throughput screen – well really medium-throughput but high-throughput for us – on Niemann-Pick Type C (NPC) patient-derived fibroblasts a couple of months back. We wanted to do a pilot screen with the Microsource bioactives...
NPC1 KO mouse brain study

NPC1 KO mouse brain study

Well it has been a little while since I wrote a post, and a lot has happened since then, which I am sure you read about in our blogs and tweets. We changed our company name, partnered with Novartis and started partnering with patient groups to engineer our organisms...
A fly model of Niemann-Pick C

A fly model of Niemann-Pick C

This post is written by Tom Hartl, PhD, our resident Drosophilist. You can follow Tom on Twitter (@hartl_tom), where he tweets about genetics and baseball. Scientists utilize an array of organisms to gain insight into the mechanisms underlying disease. Among the most...
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